The Journal of General Physiology, Vol 34, 161-166,
Copyright © 1950 by The Rockefeller University Press
THE INFLUENCE OF INSULIN ON THE RATE OF GLUCOSE OXIDATION BY PASTEURELLA PESTIS
H. B. Levine 1
1 From the Office of Naval Research, Task V, Department of Bacteriology, and United States Naval Medical Research Unit No. 1, University of California, Berkeley
The rate of oxidation of glucose by freshly harvested resting cells of P. pestis strain A-1122 was accelerated by 20 to 41 per cent in the presence of insulin. The stimulatory action was not noted when cell-free enzyme preparations were employed and was less marked after storage of cells for 3 days. Although insulin was not oxidized by the organism, the amount of oxygen consumed during the dissimilation of a unit weight of glucose was increased in the presence of the hormone.
Submitted on July 13, 1950