The Journal of General Physiology
Cell MicroControls
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The Journal of General Physiology, Vol 34, 321-323, Copyright © 1951 by The Rockefeller University Press


ARTICLE

INJURY IN RELATION TO CELL ORGANIZATION

W. J. V. Osterhout 1

1 From the Laboratories of The Rockefeller Institute for Medical Research and the Marine Biological Laboratory, Woods Hole

When a part of a Nitella cell, A, is covered with water and the rest of the cell, B, is in contact with a toxic solution there is an escape of solutes at B. This is followed by the escape of solutes at A which causes the death of A. Water enters at A, flows along inside the cell, and escapes at B carrying solutes with it. When this is prevented by covering A with mineral oil the escape of solutes at A is delayed and the life of A is correspondingly prolonged. It is remarkable that this occurs in spite of the fact that the hydrostatic pressure inside the cell (turgor) drops from 6.4 atmospheres to zero.

It would seem that A might not be affected by the death of B if the escape of solutes could be prevented.

Submitted on July 24, 1950


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