The Journal of General Physiology
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The Journal of General Physiology, Vol 34, 761-764, Copyright © 1951 by The Rockefeller University Press

ARTICLE

NUCLEIC ACID SYNTHESIS IN MUSTARD GAS-TREATED E. COLI B

Roger M. Herriott 1 and With the Technical Assistance of James L. Barlow

1 From the Department of Biochemistry, Johns Hopkins School of Hygiene and Public Health, Baltimore

Following exposure to dilute aqueous solutions of mustard gas, suspensions of E. coli B do not produce DNA although PNA is formed in nearly normal amounts. When the treated cells are infected with virus T2, DNA is synthesized and RNA is not. The DNA formation continued after the virus titer reached a maximum.

Submitted on February 3, 1951


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