The Journal of General Physiology
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The Journal of General Physiology, Vol 35, 489-493, Copyright © 1952 by The Rockefeller University Press


ARTICLE

THE ALLEGED OCCURRENCE OF ADRENALIN IN THE MEALWORM

Robert I. Gregerman 1 and George Wald 1

1 From the Biological Laboratories of Harvard University, Cambridge

Wense has reported the isolation of crystalline adrenalin from larvae of the beetle Tenebrio molitor. An attempt to repeat his procedures failed to yield any evidence of adrenalin. Analysis of mealworm extracts by paper chromatography and colorimetric means also yielded no indication of adrenalin, though adrenalin added to mealworms can be detected by these procedures in amounts less than 1 mg. per 100 gm. Mealworm extracts reveal on the paper chromatogram the presence of two other orthodiphenols, neither of which appears to be dopa but which may be 3,4-dihydroxyphenyllactic acid and 3,4-dihydroxyphenylacetic acid, compounds recently isolated elsewhere from this organism.

Submitted on July 28, 1951


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