The Journal of General Physiology
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The Journal of General Physiology, Vol 4, 639-654, Copyright © 1922 by The Rockefeller University Press

ARTICLE

THE STABILITY OF BACTERIAL SUSPENSIONS

II. THE AGGLUTINATION OF THE BACILLUS OF RABBIT SEPTICEMIA AND OF BACILLUS TYPHOSUS BY ELECTROLYTES.



John H. Northrop 1 and Paul H. De Kruif 1

1 From the Laboratories of The Rockefeller Institute for Medical Research.

1. Measurements have been made of the potential and of the cohesive force at the surface of Bacillus typhosus and the bacillus of rabbit septicemia in solutions of various salts and acids.

2. Electrolytes in low concentration (0.01 N) affect primarily the potential, and in high concentration decrease the cohesive force.

3. As long as the cohesive force is not affected, agglutination occurs whenever the potential is reduced below about 15 millivolts.

4. When the cohesive force is decreased the critical potential is also decreased, and in concentrated salt solution no agglutination occurs even though there is no measurable potential.

Submitted on May 22, 1922


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