The Journal of General Physiology
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The Journal of General Physiology, Vol 48, 375-378, Copyright © 1964 by The Rockefeller University Press

ARTICLE

Ion Transport in Isolated Rabbit Ileum

III. Chloride fluxes



Stanley G. Schultz 1, Ralph Zalusky 1, and Arthur E. Gass Jr. 1

1 From the Bionucleonics Department, United States Air Force School of Aerospace Medicine, Brooks Air Force Base, Texas.

Dr. Schultz's present address is the Biophysical Laboratory, Harvard Medical School, Boston. Dr. Zalusky's present address is the Department of Hematology, Mount Sinai Hospital, New York

Unidirectional Cl fluxes across in vitro segments of rabbit ileum have been determined both in the absence and in the presence of an electrochemical potential gradient. The results indicate that Cl transport in this preparation can be attributed to purely passive forces uninfluenced by solvent drag or exchange diffusion. Furthermore, on the basis of this and previous studies, it has been demonstrated that the sum of the partial ionic conductances of Na and Cl accounts for at least 90 per cent of the total tissue conductance.

Submitted on May 18, 1964


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