The Journal of General Physiology
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The Journal of General Physiology, Vol 49, 681-687, Copyright © 1966 by The Rockefeller University Press


ARTICLE

Diffusivity Measurements of Human Methemoglobin

K. H. Keller 1 and S. K. Friedlander 1

1 From the Department of Chemical Engineering, The Johns Hopkins University, Baltimore.

Dr. Keller's present address is the Department of Chemical Engineering, University of Minnesota, Minneapolis. Dr. Friedlander's present address is the W. M. Keck Engineering Laboratories, California Institute of Technology, Pasadena

Experimental measurements of the diffusion coefficient of human methemoglobin were made at 25°C with a modified Stokes diaphragm diffusion cell. A Millipore filter was used in place of the ordinary fritted disc to facilitate rapid achievement of steady state in the diaphragm. Methemoglobin concentrations varied from approximately 5 g/100 ml to 30 g/100 ml. The diffusion coefficient in this range decreased from 7.5 x 10-7 cm2/sec to 1.6 x 10-7 cm2/sec.

Submitted on May 21, 1965


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