The Journal of General Physiology
Avanti Polar Lipids
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The Journal of General Physiology, Vol 49, 331-346, Copyright © 1966 by The Rockefeller University Press

APPROACHES TO THE BIOSYNTHESIS OF MACROMOLECULES

Polysaccharide Biosynthesis

P. W. Robbins 1, A. Wright 1, and M. Dankert 1

1 From the Division of Biochemistry, Massachusetts Institute of Technology, Cambridge

Polysaccharide synthesis is discussed from the point of view of the sources of biological information that determine the structures and control the rates of synthesis of complex polysaccharides. It is concluded that three types of information contribute in important and different ways, namely enzyme specificity, primer substances, and the structure of the cytoplasmic membrane. Each of these factors is discussed in a general way with examples of its contribution to the structure and organization of specific polysaccharides.


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P. W. Robbins, D. Bray, M. Dankert, and A. Wright
Direction of Chain Growth in Polysaccharide Synthesis: Work on a bacterial polysaccharide suggests that elongation can occur at the "reducing" end of growing chains
Science, December 22, 1967; 158(3808): 1536 - 1542.
[Abstract] [PDF]


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