The Journal of General Physiology
World Precision Insruments
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF, 1022K)
Right arrow Alert me when this article is cited
Right arrow Citation Map
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new content in the JGP
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Alving, B. O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Alving, B. O.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of General Physiology, Vol 51, 29-45, Copyright © 1968 by The Rockefeller University Press

ARTICLE

Spontaneous Activity in Isolated Somata of Aplysia Pacemaker Neurons

Barbara O. Alving 1

1 From the Section on Spinal Cord, Laboratory of Neurophysiology, National Institute of Neurological Diseases and Blindness, National Institutes of Health, Bethesda, Maryland 20014

Somata of pacemaker and nonpacemaker neurons were isolated by ligatures tied around the axons between the somata and the synaptic regions, and the transmembrane potentials of the isolated somata were recorded. Isolated somata of pacemaker neurons had a spontaneous discharge while isolated somata of nonpacemaker neurons were quiescent. In addition, the time course of accommodation in isolated somata of pacemaker and nonpacemaker neurons was found to be different. In pacemaker neurons, injection of current produced a change in rate of discharge sustained for the duration of current injection, while in nonpacemakers, current injection produced only a transient change in discharge rate. Evidence is presented that the pacemaker locus and spike trigger zone in the intact pacemaker neuron are located on the soma.

Submitted on October 21, 1966


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J. Neurophysiol.Home page
C. G. Evans, B. Ch. Ludwar, and E. C. Cropper
Mechanoafferent Neuron With An Inexcitable Somatic Region: Consequences for the Regulation of Spike Propagation and Afferent Transmission
J Neurophysiol, April 1, 2007; 97(4): 3126 - 3130.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. Hausser, I. M. Raman, T. Otis, S. L. Smith, A. Nelson, S. du Lac, Y. Loewenstein, S. Mahon, C. Pennartz, I. Cohen, et al.
The Beat Goes On: Spontaneous Firing in Mammalian Neuronal Microcircuits
J. Neurosci., October 20, 2004; 24(42): 9215 - 9219.
[Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. J. Susswein, I. Hurwitz, R. Thorne, J. H. Byrne, and D. A. Baxter
Mechanisms Underlying Fictive Feeding in Aplysia: Coupling Between a Large Neuron With Plateau Potentials Activity and a Spiking Neuron
J Neurophysiol, May 1, 2002; 87(5): 2307 - 2323.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
L. Silva, Y Amitai, and B. Connors
Intrinsic oscillations of neocortex generated by layer 5 pyramidal neurons
Science, January 25, 1991; 251(4992): 432 - 435.
[Abstract] [PDF]

Home page
 ScienceHome page
W. Wilson and H Wachtel
Prolonged inhibition in burst firing neurons: synaptic inactivation of the slow regenerative inward current
Science, November 17, 1978; 202(4369): 772 - 775.
[Abstract] [PDF]

Home page
 ScienceHome page
M. Thomas and A. Gorman
Internal calcium changes in a bursting pacemaker neuron measured with arsenazo III
Science, April 29, 1977; 196(4289): 531 - 533.
[Abstract] [PDF]


  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents