The Journal of General Physiology
World Precision Insruments
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF, 1072K)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new content in the JGP
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Eisenberg, R. S.
Right arrow Articles by Gage, P. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Eisenberg, R. S.
Right arrow Articles by Gage, P. W.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of General Physiology, Vol 53, 279-297, Copyright © 1969 by The Rockefeller University Press

ARTICLE

Ionic Conductances of the Surface and Transverse Tubular Membranes of Frog Sartorius Fibers

Robert S. Eisenberg 1 and Peter W. Gage 1

1 From the Department of Physiology, Duke University, Durham, North Carolina 27706.

Dr. Eisenberg's present address is Department of Physiology, University of California at Los Angeles, Los Angeles, California 90024. Dr. Gage's present address is Department of Physiology, University of New South Wales, Kensington, Australia

The resting ionic conductances of frog sartorius muscle fibers have been determined in a variety of conditions in order to measure the potassium conductance of the tubular and surface membranes (gKt and gKs) and the chloride conductance of the tubular and surface membranes (gClt and gCls). In both normal fibers and fibers without tubules, measurements of input resistance and diameter were made at normal pH and at low pH when the chloride conductance was very small. These measurements permitted the separation of the ionic conductances: gCls = 219 µmhos/cm2; gClt = 0 µmhos/cm2; gKs = 28 µmhos/cm2; gKt = 55 µmhos/cm2. Possible sources of systematic error are discussed and a statistical analysis of the effects of random error is presented. The implications of the nonuniformity of membrane properties are discussed along with possible anatomical explanations.

Submitted on October 25, 1968


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J. Physiol.Home page
T. L. Dutka, R. M. Murphy, D. G. Stephenson, and G. D. Lamb
Chloride conductance in the transverse tubular system of rat skeletal muscle fibres: importance in excitation-contraction coupling and fatigue
J. Physiol., February 1, 2008; 586(3): 875 - 887.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
J. A. Fraser and C. L.-H. Huang
A quantitative analysis of cell volume and resting potential determination and regulation in excitable cells
J. Physiol., September 1, 2004; 559(2): 459 - 478.
[Abstract] [Full Text] [PDF]

Home page
 JGPHome page
B. S. Launikonis and D. G. Stephenson
Osmotic Properties of the Sealed Tubular System of Toad and Rat Skeletal Muscle
J. Gen. Physiol., February 23, 2004; 123(3): 231 - 247.
[Abstract] [Full Text] [PDF]

Home page
 Cold Spring Harb Symp Quant BiolHome page
L. D. Peachey
Electrical Events in the T-System of Frog Skeletal Muscle
Cold Spring Harb Symp Quant Biol, January 1, 1973; 37(0): 479 - 487.
[Abstract] [PDF]


  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents