The Journal of General Physiology
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The Journal of General Physiology, Vol 9, 211-215, Copyright © 1925 by The Rockefeller University Press

ARTICLE

THE EFFECT OF RADIOACTIVE RADIATIONS AND X-RAYS ON ENZYMES

IV. THE EFFECT OF RADIATIONS FROM RADIUM EMANATION ON SOLUTIONS OF INVERTASE.



Raymond G. Hussey 1 and William R. Thompson 1

1 From the Laboratory of Biophysical Research, Department of Pathology, Cornell University Medical School, and The Memorial Hospital, New York.

The radiochemical inactivation of invertase by beta radiation from the radioactive products in equilibrium with radium emanation can be explained quantitatively on the same basis as that of trypsin and pepsin previously reported; namely, the rate of change in the logarithm of the concentration of the active enzyme with respect to the variable, W, is constant, under the conditions of irradiation described, when the volume of solution exposed is constant. When, within the limits stated in this paper, this volume (V) is varied, the rate of radiochemical change is inversely proportional to V; i.e.,

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Accepted on August 5, 1925


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