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Cover picture:
Cartoon of the reaction cycle of SERCA Ca2+-ATPase, based on crystal structures of its four principal
conformations: during a complete cycle, two cytoplasmic Ca2+ ions are extruded into the lumen of the sarcoplasmic
reticulum in exchange for two protons, at the expense of hydrolysis of a single molecule of ATP (C. Toyoshima, with
permission).
[Table of Contents]
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