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Cover picture: (Left) During depolarization, the activation of DHPRs, followed by calcium release from RyRs (fast) would also stimulate PLCs through Gi protein. The produced IP3 reaches IP3Rs on the SR and leads to calcium release (slow). (Right) The mini-dystrophin protein would repress the activity of PLC via the Gi protein and reduce the release from IP3Rs (see article by Balghi et al., 171-182.)
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