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Cover picture: Kinetic scheme for the NaPi-II transport cycle based on voltage clamp fluorometry (top). The largest change in fluorescence (ΔF) is associated with occupancy of states 1 and 8. Simulated ΔF in response to membrane voltage and Na+ ions (left), when replotted as a function of [Na] reflects cooperative binding of 2 Na+ ions (right) (see article by Virkki et al., 539–555).
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