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Cover picture: Absense of dystrophin in skeletal muscle cells causes disruption in localization and kinetic properties of Nav1.4 ion channels. (Top) Images of Nav1.4 immunofluorescence in single C57BL/6J (left) and mdx5cv (right) fibers show disruption in a longitudinally striated pattern in mdx. (Bottom) Representative traces of cell-attached Na+ currents in control (left) and mdx (right) fibers show increased activity and prolonged inactivation in mdx cells (see article by Hirn et al., 199–208).
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